The ability to detect protein-based biomarkers, which are linked to different diseases like colorectal cancer, is very important as a diagnostic tool. Usually complex biological samples like blood are studied which will contribute to different technical issues when performing an assay. The aim with the project is to optimize and develop the high throughput protein detection technique Proximity Extension Assay, PEA, into a 96-plex panel, in hopes of discovering an expression profile for colorectal cancer. PEA was developed by Olink Bioscience and allows specific proteins in a sample to be quantitatively transformed into nucleic acid sequences that are subsequently detected and quantified with real-time PCR. Two proximity probes containing oligonucleotide sequences bind pairwise to target protein and when brought in proximity, a DNA polymerase will extend a hybridization arm from one probe over to the second forming a double-stranded DNA sequence that can serve as a template in real-time PCR.

This thesis examines the effects of proximity operators and query expansion with synonyms on retrieval performance. The queries were expanded with synonyms and structured with proximity operators where the permitted distance between terms varied from 1 to 3. The expansion terms were selected from the online lexical reference system WordNet. Initial query terms were selected from 28 topics that contained compound words and were chosen on the basis of their expandibility. The English morphological analyser ENGTWOL was used for normalization of query terms.

The municipality of Sandviken is in a state of strong growth. This affects the need for more hotel rooms in Sandviken, in a way that it?s profitable to invest in a new hotel. Sandvikens largest company, the steal industry Sandvik AB, grows just like Sandviken, and have great influence on the need of more hotel rooms. Today there are three hotels placed in Sandviken, and these hotels aren?t enough when the pressure of hotel guests is at its top.The purpose with the project was to analyse the criteria?s that are important for localization of a new hotel in the Sandviken, and to clarify what kind of hotel Sandviken is in need of.

In Economic Geography, there has been a strong interest of how different forms of proximity impacts businesses. In addition, there is also a strong interest in business agglomeration, as a result businesses cluster together through physical proximity, networks and knowledge. In the development sector, there is a strong interest on how to best support the creations and growth of small enterprises.This essay emphasises on the business cluster formations in Katutura, a suburb to Windhoek the capital city of Namibia. It oversees the impacts of different types of cluster formations and their effects on the businesses. In addition, this essay will identify the main clusters in Katutura and state what makes them unique from each other and what is a common cluster feature.

To get rid of our dependence on fossil fuels we need to make use of renewable energy sources like wind power to a greater extent. Even though wind power is a renewable energy source it can still cause some problems for the close environment. One of the problems is shadow flickering. When the sun is low and the wind blows in a direction so that the rotor blades are positioned at right angles to the sunbeams and ?cut? the sunbeams off.

In this thesis I have done a discourse analysis of the documentary movie A Jihad for Love. A Jihad for Love came out 2007 and is directed by Parvez Sharma. The documentary movie is about homosexual Muslims and their jihad, struggle, for love and to be accepted in a world where they are barely recognized as a group. My aim of the thesis was to see how the movie portrays the persons who are in the film and their relationship to Islam and who gets access to the religion. I have also analyzed if Islam can be used to strengthen the sexual identity or if it works in the opposite way.

The purpose of this thesis is to examine the performance of different types of queries in the AltaVista query-based search engine. Thirty information needs have been collected from an ask-a-question service on the World Wide Web, which means that they are based on real users information needs. This is done to avoid partiality in the study. The author has invented different types of queries for each and every one of the information needs in accordance with the search syntax available for AltaVista. The types used are Boolean expressions, queries including proximity operators, phrases and queries directed towards a specific field.

Det finns många faktorer som påverkar hur svårlöst en konflikt är. Vi undersöker en av dem, nämligen skuggnätverken, genom att titta på kausalsambandet mellan skuggnätverk och staters olika uppbyggnadsprocesser. Begreppet skuggnätverk är en adaption av Nordstroms ?shadows? ? det vill säga ekonomiska och politiska länkar som på både lokal och internationell nivå rör sig utanför de statliga direktiven. Genom att studera skuggnätverkens utbredning i fyra afrikanska länder: Sydafrika, Kongo, Angola och Sierra Leone, ser vi de effekter som de har haft på de ekonomiska, politiska och sociala områdena i respektive länder.

This paper is about a new organization how to get smaller communities to join together and become much larger. The purpose is to find out why Norra Sandsjö community and Bringetofta and Norra Sandsjö parishes were separated when Sävsjö municipality block was formed. The purpose is further to find out what the councils of Norra Sandsjö, Nässjö and Sävsjö, the church council and the people who lived in the area thought about the decision that was made by the executive organization in this matter (länsstyrelsen in Jönköping). Voting was arranged amongst the people, who lived in the specific area that in the first inquiry was suggested to be connected with Nässjö municipality block. The source material gives the result of this voting and the opinions of Norra Sandsjö, Nässjö and Sävsjö communities in this question.

City of Malmö has ambitions for the district Hyllie to become a demonstrative area ofsustainable urban development. As a part of this the following report aims to investigate the potential in using noise barriers combined with photovoltaics along Annetorpsvägen to generate solar electricity. To quantify the losses that shadows from buildings along the roadmight cause, a 3D-model of the area was constructed in SketchUp. This digital model made it possible to simulate shadows and how they change over the year. A reference model of a photovoltaic noise barrier (PVNB) was constructed and used to find the dates on which the solar cells are shadowed depending on building heights and positioning of the barrier.The results show that two lengths with a total distance of 400 meters is appropriate for applying photovoltaic noise barriers.

In the dog-human relationship humans are the ones who provide the dog with safety and comfort. Ainsworth's Strange Situation Procedure (ASSP), which was originally developed in humans to study the relationship between mothers and infants, has been modified to investigate the emotional bond research dogs have to a familiar person. Twelve research dogs were tested to investigate whether the dogs performed any behaviours indicating a secure-base effect, such as more exploration and play in the presence of a familiar person and proximity-seeking behaviours when this person is or has been absent. In the ASSP the dog enters a room with a familiar person, is introduced to a stranger, is left alone for a short period of time and experiences moments of separation and reunion. A second variation of the ASSP was added where the familiar person was replaced by another, to the dog, unfamiliar person.

Ambient Occlusion är en teknik för ambient ljussättning i digitala tredimensionella scener. Sådana scener ljussätts vanligtvis med en konstant mängd ambient ljus på samtliga ytor oberoende av ytornas vinkel och position gentemot olika ljuskällor i scenen. Detta ger ett platt och kalt intryck och utan vidare ljussättningstekniker är det ytterst svårt att urskönja detaljer i scenen. Ambient Occlusion åthjälper detta genom att reducera mängden ambient ljus i vissa delar av scenen. Ambient ljus är en enkel approximation av det reflekterade diffusa ljuset som antas nå nästan överallt i scenen.

Intermodulated force microscope (ImAFM) is a type of dynamic AFM. ImAFM opens up possibilities for mapping the topography and making quantitative determinations of material parameters at the same time. With increased information the need to generate more informative images of the sample emerges. In this Bachelor's degree project I have created tools for rendering images of a sample. The topography is plotted as the height and a material parameter is color coded on topography.

The current debate about environment and climate change has contributed to more andmore investment in alternative energy sources such as wind, solar and biogas. The Swedish Parliament has set the target that wind power should supply 10 TWh in 2015.In Sweden, wind power establishment began in the early 1980s. Since then the development has gained a tremendous momentum. The purpose of this study was to find out what problems wind power brings and what power relations that exists in connection with wind power establishment and how the landscape is affected by windpower construction, focusing on some cases in Falkenberg and Varberg. This study shows that wind power establishment is a very complicated process.

The purpose of this thesis was to increase the understanding and discuss safety aspects in two stairwells on Nyforsgatan in Eskilstuna, where the buildings were built during the years 1965-1975. I have presented a proposal for improvement through lighting. I have through different methods, such as surveys, interviews, literature studies and observations, come to a conclusion: that there are opportunities for improvement through better lighting that allows orientation in space and creates a nice atmosphere which will remove the feeling of not being safe, e.g. dark corners and shadows. It has been an exciting process to gather enough of facts to rely on and to develop the lighting design for the environments.